Measuring the impact of your cosmetic products on the oral microbiome
Oral microbiome and cosmetics
Enhance the scientific value of your products and ingredients
Why analyze the oral microbiome?
Understanding the oral microbiome
The oral microbiome is a complex, living ecosystem composed of more than 700 microbial species (bacteria, yeasts, viruses, archaea, etc.).
Dominated by genera such as Streptococcus, Veillonella, and Lactobacillus, it plays an essential role in oral health: (1,2).
- It participates in digestion and protection against pathogens,
- It helps prevent cavities, gingivitis, and periodontitis, (3)
- It interacts with the rest of the body through the mouth-gut-immune system axis.
- Its balance depends on many factors: diet, hygiene and products used, medications, age, and lifestyle habits.
Formulating with respect for this balance means designing differently: safer, better tolerated, and scientifically based products.
Sources :
1. Santacroce L, Passarelli PC, Azzolino D, Bottalico L, Charitos IA, Cazzolla AP, et al. Oral microbiota in human health and disease: A perspective. Exp Biol Med Maywood NJ. août 2023;248(15):1288‑301.
2. Baker JL, Mark Welch JL, Kauffman KM, McLean JS, He X. The oral microbiome: diversity, biogeography and human health. Nat Rev Microbiol. févr 2024;22(2):89‑104.
3. Hampelska K, Jaworska MM, Babalska ZŁ, Karpiński TM. The Role of Oral Microbiota in Intra-Oral Halitosis. J Clin Med. 2 août 2020;9(8):2484.
Measuring the impact of your product on the oral microbiome
Product impact: what to avoid
Overly aggressive agents → imbalance (dysbiosis), decline in protective commensals, rebound of opportunistic strains.
What to look for
Effective but selective formulas that respect key commensals and limit the increase in dysbiosis indicators (acidogenic load, pathogenic biofilm, etc.).
How can this be proven?
We perform in vitro tests on strains representative of the oral microbiome to measure:
- Respect for this fragile ecosystem
- The potential probiotic, bactericidal, or regulatory effects of your products
- Or explore the impact of active ingredients on target strains such as Streptococcus mutans or P. gingivalis.
What BYOME LABS does
- In vitro cultures of strains representative of the human oral microbiome
- Simulation of specific dysbiosis: halitosis, gingivitis, etc.
Customized testing for your oral care products, active ingredients, or cosmetic formulas
Our comprehensive reports can be used by your R&D, marketing, and regulatory teams to support your claims:
“Respects the balance of the oral microbiome”
“Tested on the oral microbiome”
“Microbiome-friendly – gentle formula for oral flora”
“Helps restore microbial balance in cases of dysbiosis (halitosis, tartar, cavities)”
With 20 years of expertise in microbiology, BYOME LABS has mastered the cultivation of demanding microorganisms and can help you transform your scientific evidence into a concrete competitive advantage.
FAQ – Frequently asked questions about cosmetic brands
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What is the oral microbiome?
This refers to all the microorganisms naturally present in the mouth. It plays a key role in oral health and immune protection.
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Which products can be tested?
Any cosmetic or hygiene product applied in the mouth: toothpastes, mouthwashes, gels, elixirs, sprays, etc.
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How long does it take to get the results?
Between 10 and 30 working days depending on the formula tested. We adapt the protocols to your deadlines.
What types of cosmetic products can be tested on the oral microbiome?
We analyze the microbiome impact of all types of oral care products and ingredients:
- Toothpastes (gels, pastes, powders, solids)
- Mouthwash solutions, oral sprays…
- Soothing gingival gels
- Active ingredients for oral hygiene
Our expertise is tailored to your specific formulations and challenges.
French expertise dedicated to oral cosmetics professionals
BYOME LABS is a French deep tech company specializing in microbiome analysis applied to cosmetics.
We collaborate with key players in the cosmetics and oral hygiene industries:
- R&D laboratories of cosmetic brands
- Formulators specializing in dental hygiene
- Suppliers of active ingredients for oral care
- Manufacturers and subcontractors in oral cosmetics
R&D Center & Microbiology Laboratory in Clermont-Ferrand
Our approach is 100% professional, scientific, and customized.
Your tangible benefits
Partnering with BYOME LABS means:
- Scientifically demonstrating that your oral care products respect the microbiome
- Positioning yourself as an expert, innovative, and responsible brand
- Gaining a competitive advantage in a saturated market
- Accessing valid microbiome-friendly claims for your regulatory submissions
- Benefiting from a fast, reliable, French-made analysis and personalized support
Get your oral care formulas tested today
Vous développez une gamme d’hygiène buccale ?
Are you developing an oral hygiene range? Have its respect for the oral microbiome validated by an expert laboratory.
Proof. Science. A competitive advantage.
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Microbiome buccal et pharmaceutique