Oral microbiome and cosmetics

Measuring the impact of your cosmetic products on the oral microbiome

Enhance the scientific value of your products and ingredients

Why analyze the oral microbiome?

Understanding the oral microbiome

The oral microbiome is a complex, living ecosystem composed of more than 700 microbial species (bacteria, yeasts, viruses, archaea, etc.).

Dominated by genera such as Streptococcus, Veillonella, and Lactobacillus, it plays an essential role in oral health: (1,2).

It participates in digestion and protection against pathogens,
It helps prevent cavities, gingivitis, and periodontitis, (3)
It interacts with the rest of the body through the mouth-gut-immune system axis.

Its balance depends on many factors: diet, hygiene and products used, medications, age, and lifestyle habits.

Formulating with respect for this balance means designing differently: safer, better tolerated, and scientifically based products.

Sources :

Santacroce L, Passarelli PC, Azzolino D, Bottalico L, Charitos IA, Cazzolla AP, et al. Oral microbiota in human health and disease: A perspective. Exp Biol Med Maywood NJ. août 2023;248(15):1288‑301.
Baker JL, Mark Welch JL, Kauffman KM, McLean JS, He X. The oral microbiome: diversity, biogeography and human health. Nat Rev Microbiol. févr 2024;22(2):89‑104.
Hampelska K, Jaworska MM, Babalska ZŁ, Karpiński TM. The Role of Oral Microbiota in Intra-Oral Halitosis. J Clin Med. 2 août 2020;9(8):2484.

Measuring the impact of your product on the oral microbiome:

Product impact: what to avoid
Overly aggressive agents → imbalance (dysbiosis), decline in protective commensals, rebound of opportunistic strains.

What to look for
Effective but selective formulas that respect key commensals and limit the increase in dysbiosis indicators (acidogenic load, pathogenic biofilm, etc.).

How can this be proven?
We perform in vitro tests on strains representative of the oral microbiome to measure:

Respect for this fragile ecosystem

The potential probiotic, bactericidal, or regulatory effects of your products

Or explore the impact of active ingredients on target strains such as Streptococcus mutans or P. gingivalis.

Témoignages

“BYOME LABS assisted us in evaluating the microbiome impact of a new ingredient. The process was clear from start to finish, and the results allowed us to make more informed formulation decisions. The team is very responsive and informative, which made the collaboration truly enjoyable. We would not hesitate to use their services again.”

Marie, distributor of specialty ingredients

“Working with Byome Labs has been a real added value for our brand. Thanks to their precise analyses and expertise in microbiology, we have been able to test our products and obtain the ‘Microbiome Friendly’ label, which reinforces our credibility in the marketplace. Their strategic vision and marketing skills helped us turn scientific data into convincing arguments for our customers. A smooth and rewarding collaboration that clearly made all the difference! “

Sandra, DEMAIN BEAUTY

“Obtaining the Microbiome Respect label with the support of BYOME LABS was a real asset for our launch. Their team guided us at every stage, from testing to understanding the results, always with a clear and effective approach. This label strengthened our consumers’ trust and clearly differentiated our product in a highly competitive market. A simple, rigorous, and effective collaboration.”

Coralie Sabatier, BOPLUME

Sébastien, cosmetics group

What BYOME LABS does

In vitro cultures of strains representative of the human oral microbiome
Simulation of specific dysbiosis: halitosis, gingivitis, etc.

Customized testing for your oral care products, active ingredients, or cosmetic formulas

Our comprehensive reports can be used by your R&D, marketing, and regulatory teams to support your claims:

“Respects the balance of the oral microbiome”
“Tested on the oral microbiome”
“Microbiome-friendly – gentle formula for oral flora”
“Helps restore microbial balance in cases of dysbiosis (halitosis, tartar, cavities)”

With 20 years of expertise in microbiology, BYOME LABS has mastered the cultivation of demanding microorganisms and can help you transform your scientific evidence into a concrete competitive advantage.

FAQ

FAQ – Frequently asked questions about cosmetic brands

What is the oral microbiome? +

This refers to all the microorganisms naturally present in the mouth. It plays a key role in oral health and immune protection.

Which products can be tested? +

Any cosmetic or hygiene product applied in the mouth: toothpastes, mouthwashes, gels, elixirs, sprays, etc.

How long does it take to get the results? +

Between 10 and 30 working days depending on the formula tested. We adapt the protocols to your deadlines.

Thanks to our trusted partners

Contact us

Would you like to make an appointment or get more information?

You can reach us by filling in the contact form opposite or by e-mail at : info@byomelabs.com

BYOME LABS

Cité de l’Innovation
7 rue Auguste Rodin
28630 LE COUDRAY

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What types of cosmetic products can be tested on the oral microbiome?

We analyze the microbiome impact of all types of oral care products and ingredients:

• Toothpastes (gels, pastes, powders, solids)

• Mouthwash solutions, oral sprays…

• Soothing gingival gels

• Active ingredients for oral hygiene

Our expertise is tailored to your specific formulations and challenges.

French expertise dedicated to oral cosmetics professionals

Your tangible benefits

Get your oral care formulas tested today

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