Skin microbiome and pharmaceuticals

Measuring the impact of your dermatological treatments on the skin microbiome

We also work with you: pharmaceutical industry

Beyond cosmetics, BYOME LABS supports R&D and regulatory teams in the pharmaceutical industry.

With 20 years of expertise in microbiology, particularly in the pharmaceutical industry, we conduct studies within a strict and regulated framework for products that come into contact with the skin microbiome.

We also work on medical devices and various galenic formulations (wipes, gels, solutions, creams, etc.).

Our goal: to produce robust and reliable evidence to support your decisions.

Notre méthodologie :

At BYOME LABS, we exclusively perform in vitro tests based on culturomics.

Work on living microorganisms

Culture of bacteria organized in biofilm, best reflecting real-world conditions

In vitro cultures with wild or reference strains

Reproduction of balanced and unbalanced microbiomes

Ability to reproduce targeted dysbiosis (acne, atopic dermatitis, etc.) in vitro to evaluate the corrective effect of products

Customized tests tailored to pharmaceutical treatments and ingredients

Témoignages

Towards microbiome-guided therapies

As research on the microbiome progresses, new therapeutic approaches are emerging. By modulating these microbial communities, it is becoming possible to consider innovative strategies for preventing and treating many diseases, whether acute or chronic. These advances underscore the importance of preserving this microbial balance to promote optimal health (Hou K et al. 2022, Choi I et al. 2012).

For laboratories and pharmaceutical manufacturers, understanding and positively influencing this balance is essential to optimize the action of topical treatments and limit adverse effects.

Switch to in vitro microbiome analysis

Are you developing an innovative dermatological treatment or a pharmaceutical active ingredient?
Contact BYOME LABS for a personalized and scientifically validated protocol.

FAQ

Frequently asked questions

Why test a treatment on the skin microbiome? +
To prove that it respects or restores the skin's balance, improves its effectiveness, and minimizes adverse effects.
Can you simulate a skin condition? +
Yes, we reproduce imbalances such as acne or atopic dermatitis in vitro to measure the corrective effect.
How long does it take to get the results? +
On average, 2 to 4 weeks depending on the protocol.

Thanks to our trusted partners

Contact us

Would you like to make an appointment or get more information?

You can reach us by filling in the contact form opposite or by e-mail at : info@byomelabs.com

BYOME LABS

Cité de l’Innovation
7 rue Auguste Rodin
28630 LE COUDRAY

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The link between skin microbiome and human health

The human body is a complex ecosystem hosting billions of microorganisms. The term “microbiome” refers to the totality of the genes of these microbial communities, which extend across almost every surface of the body. It is often referred to as the “second genome” because of its complementary role to that of the host. Its interactions can be beneficial, pathogenic, or neutral, thereby influencing human physiology.

With genetic diversity estimated to be between 50 and 100 times greater than that of the host, the microbiome regulates many processes (1,2).

One of the major functions of the microbiome is to protect the body against colonization by pathogens. This regulation is based on complex interactions between microorganisms, which maintain a stable balance. However, under certain conditions, beneficial bacteria can become pathogenic due to changes in the microbial environment.

Sources :

1. Hou K, Wu ZX, Chen XY, Wang JQ, Zhang D, Xiao C, et al. Microbiota in health and diseases. Signal Transduct Target Ther. 23 avr 2022;7(1):1‑28.  

2. Cho I, Blaser MJ. The human microbiome: at the interface of health and disease. Nat Rev Genet. avr 2012;13(4):260‑70.  

3. Aggarwal N, Kitano S, Puah GRY, Kittelmann S, Hwang IY, Chang MW. Microbiome and Human Health: Current Understanding, Engineering, and Enabling Technologies. Chem Rev. 11 janv 2023;123(1):31‑72. 

Testable products and applications

  • Dermatological creams and gels
  • Topical healing or antiseptic solutions
  • Wipes and bandages
  • Pharmaceutical active ingredients (probiotics, prebiotics, plant extracts, etc.)
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BYOME LABS, French expert in the pharmaceutical skin microbiome

We work with:

  • Pharmaceutical companies
  • Manufacturers of dermatological medical devices
  • Suppliers of active ingredients
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Benefits for your projects

  • Scientific evidence tailored to the pharmaceutical sector
  • Differentiation in your regulatory dossiers
  • Risk reduction in clinical development
  • Solid data for your microbiome-friendly claims
  • Assessment of the corrective effect in cases of dysbiosis
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