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Skin microbiome and cosmetics

Measuring the impact of your cosmetic products on the skin microbiome

Promote your treatments and ingredients scientifically

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Why analyze the skin microbiome?

Provide scientific evidence of the impact of your products on the skin microbiome

Brands, formulators, and ingredient suppliers are now required to prove the real impact of their products on the skin microbiome, which is key to reassuring consumers and standing out in a saturated competitive environment.

For several years now, Regulation (EU) No. 655/2013 has set clear rules: all marketing claims must be justified by verifiable evidence, whether they relate to anti-aging, sensitive skin, or microbiome compatibility.

Official text: “Claims for cosmetic products, whether explicit or implicit, shall be supported by adequate and verifiable evidence regardless of the types of evidential support used to substantiate them, including where appropriate expert assessments. […].” (Regulation (EU) No. 655/2013, Art. 3 – eur-lex.europa.eu)

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Interest in the skin microbiome is becoming widespread:

According to data from Spate (Global microbiome beauty trends in 2025 | BeautéMatter), global searches for “microbiome” have doubled in five years.

Between August 2024 and July 2025 (vs. previous year):

  • “skin + microbiome”: +176.9%, or 3,400 searches/month
  • “skin care + microbiome”: +98.2%, or 2,000 searches/month
  • “scalp + microbiome”: +120.2%, or 480 searches/month

Consumer interest extends beyond the face to scalp health and overall skin wellness.

According to Euromonitor International, consumers of beauty and personal care products in 2025 are increasingly attracted to brands with a clinical positioning and are looking for products backed by science and medicine, creating huge interest in dermocosmetics and skin health-related products.

Témoignages

“Working with Byome Labs has been a real added value for our brand. Thanks to their precise analyses and expertise in microbiology, we have been able to test our products and obtain the ‘Microbiome Friendly’ label, which reinforces our credibility in the marketplace. Their strategic vision and marketing skills helped us turn scientific data into convincing arguments for our customers. A smooth and rewarding collaboration that clearly made all the difference! “

Sandra, DEMAIN BEAUTY

“Working with Byome Labs has been a real added value for our brand. Thanks to their precise analyses and expertise in microbiology, we have been able to test our products and obtain the ‘Microbiome Friendly’ label, which reinforces our credibility in the marketplace. Their strategic vision and marketing skills helped us turn scientific data into convincing arguments for our customers. A smooth and rewarding collaboration that clearly made all the difference! “

Sandra, DEMAIN BEAUTY

“Working with Byome Labs has been a real added value for our brand. Thanks to their precise analyses and expertise in microbiology, we have been able to test our products and obtain the ‘Microbiome Friendly’ label, which reinforces our credibility in the marketplace. Their strategic vision and marketing skills helped us turn scientific data into convincing arguments for our customers. A smooth and rewarding collaboration that clearly made all the difference! “

Sandra, DEMAIN BEAUTY

BYOME LABS tests the real effect of your products on the skin microbiome

Is your product unique? So are our analyses.

Our method is based exclusively on in vitro tests using culturomics: we work directly on living microorganisms and select our strains using genomic identification data from scientific literature.

We support cosmetic, dermo-cosmetic, and pharmaceutical brands in scientifically proving their claims related to the skin microbiome. We provide you with a comprehensive report containing verified and verifiable evidence that can be used directly in your regulatory filings.

With over 20 years of experience in the microbiome and expertise in biofilm, our team helps you validate, optimize, and enhance your formulas with scientific rigor, transparency, and differentiation.

A strategic weapon for your marketing claims

Thanks to our results, you can back up your claims with concrete data:

  • “Preserves skin balance”
  • “Preserves microbial diversity”
  • “Helps reduce atopic dermatitis”
  • “Demonstrates prebiotic activity”
  • “Anti-acne effect”

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FAQ

Frequently asked questions from brands & formulators

Why test a cosmetic product on the skin microbiome? +
To ensure that it does not disrupt a healthy skin microbiome, to provide scientific evidence for your marketing claims, and to reassure consumers while differentiating yourself in a saturated market.
Can tests be performed on individual ingredients? +
Yes, we can demonstrate the effectiveness of an ingredient, objectively assess an active ingredient, characterize the impact of excipients (particularly preservatives), and evaluate white formulas and finished products.
How long does it take to get a full report? +
According to protocol, between 10 and 30 business days. Our teams adapt to your schedules.
Do you work on rinse-off products? +
Our protocols can be adjusted to specifically evaluate rinsed products, taking into account their conditions of use.

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Contact us

Would you like to make an appointment or get more information?

You can reach us by filling in the contact form opposite or by e-mail at : info@byomelabs.com

BYOME LABS

Cité de l’Innovation
7 rue Auguste Rodin
28630 LE COUDRAY

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The skin microbiome: the new revolution in cosmetics

Cosmetics are entering a new era: that of science-based products. Among scientific advances, the study of the skin microbiome is becoming increasingly important. This living ecosystem, composed of billions of microorganisms, plays a key role in the health, balance, and beauty of the skin.

Today, cosmetics brands, formulators, and ingredient suppliers are faced with a growing demand: to prove the real impact of their products on the skin microbiome.

The skin microbiome consists of bacteria, yeasts, and other microorganisms that live naturally on the skin’s surface. It forms a natural protective barrier that is essential to the proper functioning of the epidermis.

An imbalance can lead to:

  • Redness, irritation, dryness
  • Skin conditions (acne, atopic dermatitis, etc.)
  • Impaired barrier function
  • Loss of skin comfort and radiance

Which cosmetic products should be tested on the skin microbiome?

Our protocols can be adapted to all types of products, regardless of their stage of development or formulation:

  • Facial care: creams, serums, lotions, gels, etc.
  • Body care: milks, balms, oils
  • Gentle hygiene products: cleansers, soaps, deodorants
  • Active ingredients or excipients to be validated

Are you in the formulation, reformulation, or launch phase? Our tests can validate your choices, accelerate your time-to-market, and enrich your sales pitches.

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BYOME LABS, your French laboratory specializing in the skin microbiome

BYOME LABS is a French deep tech startup dedicated to microbiome analysis for cosmetics.

We collaborate with:

  • Cosmetics brands
  • Dermo-cosmetics brands
  • Pharmaceutical brands
  • Veterinary brands
  • Ingredient manufacturers
  • Distributors

We help you scientifically demonstrate that your skincare products and ingredients:

✅ Do not disrupt the skin microbiome
✅ Respect the natural microbial balance
✅ Can be positioned as microbiome-friendly
✅ Help restore microbial balance in cases of dysbiosis (acne, atopic dermatitis, etc.)

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Your concrete benefits

By testing the microbiome impact of your products with BYOME LABS, you will:

  • Obtain scientific proof for your claims
  • Stand out in a demanding and saturated market
  • Benefit from tailor-made scientific support
  • Take advantage of our dual expertise in science and marketing to facilitate your sales strategies
  • Access our “Microbiome Respect” label. We can also demonstrate that a skincare product or ingredient has a positive effect on microbial imbalance (dysbiosis), as in the case of acne or atopic dermatitis, and thus helps to restore the balance of the skin microbiome.
  • Help restore microbial balance in cases of dysbiosis (acne, atopic dermatitis, etc.)
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What we do

  • In vitro cultures with selected live strains
  • Culture of bacteria organized in biofilm, reflecting real conditions as closely as possible
  • Reproduction of balanced and unbalanced microbiomes
  • Simulation of targeted dysbiosis: acne, atopic dermatitis, etc.
  • Customized tests according to your needs (finished products or ingredients)
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What we analyze

  • Impact on the growth of commensal strains
  • Effect on the reduction of pathogenic strains
  • Ability to restore a healthy microbial balance
  • Ability to have no impact on a healthy microbiomeYou receive a clear, rigorous scientific report that can be used by your regulatory, marketing, and R&D teams.
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Have your formulas tested today

Are you developing an innovative skincare product, active ingredient, or range with a real impact?
Prove that they respect the skin microbiome with clear and rigorous data.

BYOME LABS, scientific partner to demanding cosmetics companies.

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