PRESERVING SKIN BIODIVERSITY
TOWARDS GLOBAL APPROACH TO MICROBIOME-FRIENDLY INGREDIENTS
Discover how our partnership is building the future of microbiome-friendly skincare — through science, data and innovation.
BOOK YOUR OWN INSTANT MICROBIOME ANALYSIS’ DEMO AT IFSCC CONGRESS 2025
Want to discover more abour your microbiome?
- 5-minute test
- Personalized results
- Scientific explanation on-site
Tested ingredients & formulations
WHAT WE TESTED TOGETHER
To determine the impact on biofilm preservation, we examined the potential effect of products on 10 major strains making up the healthy microbiome.
Each ingredient was applied to be tested at the final concentration (w/v) provided by IMCD. The plates were incubated during 48h to 72h to allow biofilm formation by each strain. The amount of biofilm formed in the presence of the product is then measured by numeration and compared to that formed by strains without the product (control).
Other ingredients composing the formulation (preservative and emollient (Caprylic/Capric Triglyceride*) as well as the formulation base itself, have also been tested to check their behavior towards the skin microbiome.
GLYCERIN
neutral impact, 100% microbiome-friendly
ASCORBYL TETRAISOPALMITATE
selective activity on C. granulosum, preserving beneficial strains
SODIUM HYALURONATE
targeted activity, preserving >80% of skin flora
Simplex formula and formulas with actives
confirmed tolerance on biofilms with preserved diversity
Scientific collaboration for measurable skin impact
WHY TEST INGREDIENTS ON THE MICROBIOME?
Today, consumers expect skincare that is both effective and respectful of their skin’s natural balance. But not all ingredients are microbiome-friendly. IMCD and Byome Labs have joined forces to build an indexing database of ingredient impacts, based on a rigorous in vitro biofilm testing methodology.
The aim: provide formulators with quantitative microbiome impact scores, enabling more conscious and targeted product development.
The power of biofilm testing
GO BEYOND PLANKTONIC: TEST HOW INGREDIENTS BEHAVE IN BIOFILMS
Unlike traditional testing methods, our analysis focuses on microorganisms in biofilm form, their natural state on the skin. Tested strains include Staphylococcus epidermidis, Cutibacterium acnes, Malassezia globosa and more.
Want to learn more about our BYOME DERMA our instant skin microbiome analysis and ingredient indexing solution? Discover the abstract :
“Building an indexing database: towards a global approach to Microbiome-Friendly product formulation”
Presented at COSM’ING 2025 — Authors: Stéphanie Badel-Berchoux et al.
Microbiome-safe claims for your brand
ENABLE PROVEN, SCIENCE-BACKED CLAIMS FOR YOUR INGREDIENTS
Microbiome-preserving ingredient
Maintains viable biofilm communities
Proven in vitro biofilm compatibility
Gentle, targeted action without disrupting microbial balance
Scientifically verified on 10 key skin strains
About the partnership
A STRATEGIC ALLIANCE BUILT FOR IMPACT
Since early 2024, IMCD and Byome Labs have partnered to combine ingredient expertise with state-of-the-art microbiome science. Together, we aim to set new standards for microbiome compatibility and empower formulators with measurable, actionable data. This partnership supports a shared vision: science-driven, sustainable innovation for healthy skin ecosystems.
LET’S MEET AT IFSCC!
Meet our teams at the IMCD Booth
- Discuss ingredient testing with Byome Labs
- See the latest indexed ingredients in our demo database
- Discover how to differentiate with microbiome safety
